Obstructive Sleep Apnea Screening and Effects of Surgery in Acromegaly: A Prospective Study.

ABSTRACT:

Backgruound

To identify a screening tool for obstructive sleep apnea (OSA) and evaluate the effects of endoscopic transsphenoidal surgery on improving OSA in patients with acromegaly.

Methods

We prospectively enrolled adults with acromegaly scheduled for endoscopic transsphenoidal surgery. All measurements were conducted when participants were admitted for a baseline work-up for acromegaly before surgery and surveillance approximately 3 to 6 months after surgery. Respiratory event index (REI) was used as a surrogate for apnea-hypopnea index (Trial Registration: NCT03526016).

Results

Of the 35 patients with acromegaly (median age, 47 years; 40% men; median body mass index, 24.4 kg/m2), 24 (68.6%) had OSA (REI ≥5/hour), 15 (42.9%) had moderate-to-severe OSA (REI ≥15/hou

SUBMITTER: Cho J 

PROVIDER: S-EPMC11375303 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature