IMPACT-FH Study for Implementing Innovative Family Communication and Cascade Testing Strategies for Familial Hypercholesterolemia.

ABSTRACT:

Background

Relatives of probands diagnosed with familial hypercholesterolemia (FH) should undergo cascade testing for FH.

Objectives

The purpose of this study was to evaluate probands' choices of innovative strategies to communicate their FH result with relatives and facilitate cascade testing uptake.

Methods

Probands with an FH genetic result from the MyCode Community Health Initiative could choose to share their FH result with adult blood relatives via the Family and Healthcare Professional Packet (packet), family sharing and cascade chatbots (chatbot), and/or FH Outreach and Support Program (direct contact). Cascade testing uptake was measured as reported completion of genetic or cholesterol testing. Generalized estimating equations models were used to identify fac

SUBMITTER: Jones LK 

PROVIDER: S-EPMC11375316 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature