Adverse Events in Studies of Classic Psychedelics: A Systematic Review and Meta-Analysis.

ABSTRACT:

Importance

A clear and comprehensive understanding of risks associated with psychedelic-assisted therapy is necessary as investigators extend its application to new populations and indications.

Objective

To assess adverse events (AEs) associated with classic psychedelics, particularly serious AEs (SAEs) and nonserious AEs (NSAEs) requiring medical or psychiatric evaluation.

Data sources

The search for potentially eligible studies was conducted in the Scopus, MEDLINE, PsycINFO, and Web of Science databases from inception through February 8, 2024.

Study selection

Two independent reviewers screened articles of classic psychedelics (lysergic acid diethylamide [LSD], psilocybin, dimethyltryptamine [DMT], and 5-methoxy-N,N-dimethyltryptamine [5-MeO-DMT]) involving ad

SUBMITTER: Hinkle JT 

PROVIDER: S-EPMC11375525 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature