Enabling nucleophilic reactivity in molecular calcium fluoride complexes.

ABSTRACT: Calcium fluoride is the ultimate source of all fluorochemicals. Current synthetic approaches rely on the use of HF, generated from naturally occurring fluorspar and sulfuric acid. Methods for constructing E-F bonds directly from CaF₂ have long been frustrated by its high lattice energy, low solubility and impaired fluoride ion nucleophilicity. Little fundamental understanding of the reactivity of Ca-F moieties is available to guide methodology development; well-defined molecular species containing Ca-F bonds are extremely rare, and existing examples are strongly aggregated and evidence no nucleophilic fluoride delivery. Here, by contrast, we show that by targeting anionic systems of the type [L_n(X)₂CaF]^-, monomeric calcium fluoride complexes cont

SUBMITTER: Struijs JJC 

PROVIDER: S-EPMC11375610 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature