Dataset Information

A few-shot learning framework for the diagnosis of osteopenia and osteoporosis using knee X-ray images.

ABSTRACT:

Objective

We developed a few-shot learning (FSL) framework for the diagnosis of osteopenia and osteoporosis in knee X-ray images.

Methods

Computer vision models containing deep convolutional neural networks were fine-tuned to enable generalization from natural images (ImageNet) to chest X-ray images (normal vs. pneumonia, base images). Then, a series of automated machine learning classifiers based on the Euclidean distances of base images were developed to make predictions for novel images (normal vs. osteopenia vs. osteoporosis). The performance of the FSL framework was compared with that of junior and senior radiologists. In addition, the gradient-weighted class activation mapping algorithm was used for visual interpretation.

Results

In Cohort #1, the mean accuracy (0.728) and sensitivity (0.774) of the FSL models were higher than those of the radiologists (0.512 and 0.448). A diagnostic pipeline of FSL model (first)-radiologists (second) achieved better performance (0.653 accuracy, 0.582 sensitivity, and 0.816 specificity) than radiologists alone. In Cohort #2, the diagnostic pipeline also showed improved performance.

Conclusions

The FSL framework yielded practical performance with respect to the diagnosis of osteopenia and osteoporosis in comparison with radiologists. This retrospective study supports the use of promising FSL methods in computer-aided diagnosis tasks involving limited samples.

SUBMITTER: Xie H

PROVIDER: S-EPMC11375658 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature

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Publications

A few-shot learning framework for the diagnosis of osteopenia and osteoporosis using knee X-ray images.

Xie Hua H Gu Chenqi C Zhang Wenchao W Zhu Jiacheng J He Jin J Huang Zhou Z Zhu Jinzhou J Xu Zhonghua Z

The Journal of international medical research 20240901 9

<h4>Objective</h4>We developed a few-shot learning (FSL) framework for the diagnosis of osteopenia and osteoporosis in knee X-ray images.<h4>Methods</h4>Computer vision models containing deep convolutional neural networks were fine-tuned to enable generalization from natural images (ImageNet) to chest X-ray images (normal vs. pneumonia, base images). Then, a series of automated machine learning classifiers based on the Euclidean distances of base images were developed to make predictions for nov ...[more]

PMID: 39225007

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Project description:Plant disease diagnosis with estimation of disease severity at early stages still remains a significant research challenge in agriculture. It is helpful in diagnosing plant diseases at the earliest so that timely action can be taken for curing the disease. Existing studies often rely on labor-intensive manually annotated large datasets for disease severity estimation. In order to conquer this problem, a lightweight framework named "PDSE-Lite" based on Convolutional Autoencoder (CAE) and Few-Shot Learning (FSL) is proposed in this manuscript for plant disease severity estimation with few training instances. The PDSE-Lite framework is designed and developed in two stages. In first stage, a lightweight CAE model is built and trained to reconstruct leaf images from original leaf images with minimal reconstruction loss. In subsequent stage, pretrained layers of the CAE model built in the first stage are utilized to develop the image classification and segmentation models, which are then trained using FSL. By leveraging FSL, the proposed framework requires only a few annotated instances for training, which significantly reduces the human efforts required for data annotation. Disease severity is then calculated by determining the percentage of diseased leaf pixels obtained through segmentation out of the total leaf pixels. The PDSE-Lite framework's performance is evaluated on Apple-Tree-Leaf-Disease-Segmentation (ATLDS) dataset. However, the proposed framework can identify any plant disease and quantify the severity of identified diseases. Experimental results reveal that the PDSE-Lite framework can accurately detect healthy and four types of apple tree diseases as well as precisely segment the diseased area from leaf images by using only two training samples from each class of the ATLDS dataset. Furthermore, the PDSE-Lite framework's performance is compared with existing state-of-the-art techniques, and it is found that this framework outperformed these approaches. The proposed framework's applicability is further verified by statistical hypothesis testing using Student t-test. The results obtained from this test confirm that the proposed framework can precisely estimate the plant disease severity with a confidence interval of 99%. Hence, by reducing the reliance on large-scale manual data annotation, the proposed framework offers a promising solution for early-stage plant disease diagnosis and severity estimation.

Dataset Information

A few-shot learning framework for the diagnosis of osteopenia and osteoporosis using knee X-ray images.

Objective

Methods

Results

Conclusions

Publications

A few-shot learning framework for the diagnosis of osteopenia and osteoporosis using knee X-ray images.

Similar Datasets

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