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Can Omega-3 prevent the accidence of stroke: a mendelian randomization study.


ABSTRACT: The lipid-lowering effects of Omega-3 fatty acids have been widely reported, yet their impact on ischemic stroke remains controversial. Reports on the protective effects of unsaturated fatty acids, such as Omega-6 and Omega-7, as well as saturated fatty acids in cardiovascular diseases, including hypertension and ischemic stroke, are less frequent. This study aims to identify fatty acids associated with blood pressure and ischemic stroke through Mendelian randomization. Besides, it seeks to determine whether specific fatty acids can prevent ischemic stroke by managing blood pressure and revealing the specific mechanisms of this action. This research involved downloading relevant data from websites and extracting SNPs that met the standard criteria as instrumental variables. Simultaneously,

SUBMITTER: Xi C 

PROVIDER: S-EPMC11375838 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature