Greater exposure to PM_2.5 and PM₁₀ was associated with lower corneal nerve measures: the Maastricht study - a cross-sectional study.

ABSTRACT:

Background

Epidemiological and toxicological studies indicate that increased exposure to air pollutants can lead to neurodegenerative diseases. To further confirm this relationship, we evaluated the association between exposure to ambient air pollutants and corneal nerve measures as a surrogate for neurodegeneration, using corneal confocal microscopy.

Methods

We used population-based observational cross-sectional data from The Maastricht Study including N = 3635 participants (mean age 59.3 years, 51.6% were women, and 19.9% had type 2 diabetes) living in the Maastricht area. Using the Geoscience and hEalth Cohort COnsortium (GECCO) data we linked the yearly average exposure levels of ambient air pollutants at home address-level [particulate matter with diameters of ≤ 2.5 µm

SUBMITTER: Mokhtar SBA 

PROVIDER: S-EPMC11375839 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature