The goldmine of GWAS summary statistics: a systematic review of methods and tools.

ABSTRACT: Genome-wide association studies (GWAS) have revolutionized our understanding of the genetic architecture of complex traits and diseases. GWAS summary statistics have become essential tools for various genetic analyses, including meta-analysis, fine-mapping, and risk prediction. However, the increasing number of GWAS summary statistics and the diversity of software tools available for their analysis can make it challenging for researchers to select the most appropriate tools for their specific needs. This systematic review aims to provide a comprehensive overview of the currently available software tools and databases for GWAS summary statistics analysis. We conducted a comprehensive literature search to identify relevant software tools and databases. We categorized the tools and databases

SUBMITTER: Kontou PI 

PROVIDER: S-EPMC11375927 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature