Prenatal mood and anxiety disorders and associated cytokine changes.

ABSTRACT:

Background

We examined whether women with prenatal mood and anxiety disorders would exhibit differential pro- and anti-inflammatory marker trajectories during the prenatal and postpartum periods compared to women without these disorders.

Methods

Approximately 179 pregnant women participated in a longitudinal study conducted in two urban areas. Blood samples for inflammatory markers were collected at six study visits. The Structured Clinical Interview for the DSM-IV (SCID) was administered to participants scoring above cutoffs on anxiety and depression. Pregnant women with SCID Axis I diagnoses of mood and/or anxiety disorders were compared to other participants on inflammatory markers. Multilevel modeling tested associations between SCID diagnoses and within-person interleuk

SUBMITTER: Mancuso RA 

PROVIDER: S-EPMC11375962 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature