Transcriptomic Response to Pyrethroid Treatment in Closely Related Bed Bug Strains Varying in Resistance.

ABSTRACT: The common bed bug, Cimex lectularius, is one of the main human parasites. The world-wide resurgence of this pest is mainly due to globalization, and the spread of insecticide resistance. A few studies have compared the transcriptomes of susceptible and resistant strains; however, these studies usually relied on strains originating from distant locations, possibly explaining their extended candidate gene lists. Here, we compared the transcriptomes of 2 strains originating from the same location and showing low overall genetic differentiation (FST=0.018) but varying in their susceptibility to pyrethroids, before and after insecticide exposure. In sharp contrast with previous studies, only 24 genes showing constitutive differential expression between the strains were identified. Interestingl

SUBMITTER: Haberkorn C 

PROVIDER: S-EPMC11376223 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature