Genomic epidemiology of mecC-carrying Staphylococcus aureus isolates from human clinical cases in New Zealand.

ABSTRACT: In 2011, a novel methicillin resistance gene, mecC, was described in human and bovine Staphylococcus aureus isolates. mecC-positive S. aureus is most commonly associated with livestock and wildlife populations across Europe and is particularly prevalent in hedgehogs, but only occasionally causes human infections. In this study, we characterize and investigate the origin of two human S. aureus isolates containing mecC genes from New Zealand. The two isolates were identified from patients with severe invasion infections as part of an S. aureus bacteraemia study. Whole-genome sequencing was used to characterize staphylococcal cassette chromosome mec (SCCmec) elements and perform phylogenetic comparisons with publicly available str

SUBMITTER: Miller H 

PROVIDER: S-EPMC11376224 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature