Early goal-directed renal replacement therapy in severe pneumonia associated acute kidney injury.

ABSTRACT:

Introduction

Severe pneumonia is a crucial issue in the development of acute kidney injury (AKI). This study evaluated the efficacy of early goal-directed renal replacement therapy (GDRRT) for the treatment of severe pneumonia-associated AKI.

Methods

In this real-world retrospective cohort study, we recruited 180 patients with severe pneumonia who were hospitalized and received GDRRT in a third-class general hospital in East China between January 1, 2017, and December 31, 2021. Clinical data on baseline characteristics, biochemical indicators, and renal replacement therapy were collected. Patients were divided into Early and Late RRT groups according to fluid status, inflammation progression, and pulmonary radiology. We investigated in-hospital all-cause mortality (primary e

SUBMITTER: Yusufu A 

PROVIDER: S-EPMC11376310 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature