Comparison of intravenous versus perineural dexamethasone as a local anaesthetic adjunct for peripheral nerve blocks in the lower limb: A meta-analysis and systematic review.

ABSTRACT:

Background

As a local anaesthetic adjunct, the systemic absorption of perineural dexamethasone in the lower limb could be restricted because of decreased vascularity when compared with the upper limb.

Objectives

To compare the pharmacodynamic characteristics of intravenous and perineural dexamethasone in the lower limb.

Design

Systematic review of randomised controlled trials with meta-analysis.

Data sources

Systematic search of Central, Google Scholar, Ovid Embase and Ovid Medline to 18 July 2023.

Eligibility criteria

Randomised controlled trials, which compared the intravenous with perineural administration of dexamethasone as a local anaesthetic adjunct in peripheral nerve blocks for surgery of the lower limb.

Results

The most common peripheral

SUBMITTER: Desai N 

PROVIDER: S-EPMC11377050 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature