Mild therapeutic hypothermia after cardiac arrest - effect on survival with good neurological outcome outside of randomised controlled trials: A registry-based analysis.

ABSTRACT:

Background

For nearly 20 years, in international guidelines, mild therapeutic hypothermia (MTH) was an important component of postresuscitation care. However, recent randomised controlled trials have questioned its benefits. At present, international guidelines only recommend actively preventing fever, but there are ongoing discussions about whether the majority of cardiac arrest patients could benefit from MTH treatment.

Objective

The aim of this study was to compare the outcome of adult patients treated with and without MTH after cardiac arrest.

Design

Observational cohort study.

Setting

German Resuscitation Registry covering more than 31 million inhabitants of Germany and Austria.

Patients

All adult patients between 2006 and 2022 with out-of-hospital

SUBMITTER: Knapp J 

PROVIDER: S-EPMC11377051 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature