The effect of niacin on inflammatory markers and adipokines: a systematic review and meta-analysis of interventional studies.

ABSTRACT:

Purpose

Niacin (nicotinic acid), known for its lipid-modifying effects, has been explored for its potential anti-inflammatory properties and potential to affect adipokines secretion from adipose tissue. The aim of this systematic review and meta-analysis was to assess the effects of niacin on inflammatory markers and adipokines.

Methods

A comprehensive search was conducted across five databases: PubMed, Scopus, Cochrane Library, Embase, and ISI Web of Science. Randomized controlled trials exploring the effects of niacin on inflammatory markers (CRP, IL-6, TNF-α) and adipokines (Adiponectin, Leptin) were included. Pooled effect sizes were analysed using a random-effects model, and additional procedures including subgroup analyses, sensitivity analysis and dose-response analys

SUBMITTER: Rad EY 

PROVIDER: S-EPMC11377601 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature