Plasma Biomarkers of Traumatic Brain Injury in Adolescents With Sport-Related Concussion.

ABSTRACT:

Importance

Blood-based biomarkers may clarify underlying neuropathology and potentially assist in clinical management of adolescents with sport-related concussion (SRC).

Objective

To investigate the association between SRC and plasma biomarkers in adolescents.

Design, setting, and participants

Prospective cohort study in Canadian sport and clinic settings (Surveillance in High Schools and Community Sport to Reduce Concussions and Their Consequences study; September 2019 to November 2022). Participants were a convenience sample of 849 adolescent (ages 10-18 years) sport participants with blood samples. Data were analyzed from February to September 2023.

Exposures

Blood collection and clinical testing preseason (uninjured) and post-SRC follow-ups (ie, ≤72 hours,

SUBMITTER: Tabor JB 

PROVIDER: S-EPMC11378000 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature