Balloon Angioplasty vs Medical Management for Intracranial Artery Stenosis: The BASIS Randomized Clinical Trial.

ABSTRACT:

Importance

Previous randomized clinical trials did not demonstrate the superiority of endovascular stenting over aggressive medical management for patients with symptomatic intracranial atherosclerotic stenosis (sICAS). However, balloon angioplasty has not been investigated in a randomized clinical trial.

Objective

To determine whether balloon angioplasty plus aggressive medical management is superior to aggressive medical management alone for patients with sICAS.

Design, setting, and participants

A randomized, open-label, blinded end point clinical trial at 31 centers across China. Eligible patients aged 35 to 80 years with sICAS defined as recent transient ischemic attack (<90 days) or ischemic stroke (14-90 days) before enrollment attributed to a 70% to 99% atheros

SUBMITTER: Sun X 

PROVIDER: S-EPMC11378071 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature