Overgeneralization of conditioned fear in patients with social anxiety disorder.

ABSTRACT:

Introduction

While abnormal responses to threat, including overgeneralization to conditioned fear, have been postulated to play a critical role in pathological anxiety, the relevance of previous findings to social anxiety disorder (SAD) is unclear. We investigated conditioned and generalized fear responses in patients with SAD using socially relevant stimuli.

Methods

A total of 26 patients with SAD and 25 healthy controls participated in a fear conditioning and generalization paradigm consisting of two neutral faces as conditioned stimuli (CS+ or CS-) and an angry face with contemptuous comments as unconditioned stimuli. Eight morphed faces of two conditioned stimuli in each continuum were given to test generalization. Behavioral data and physiological responses were acquire

SUBMITTER: Lee YI 

PROVIDER: S-EPMC11378195 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature