Risk factor differences in five-year progression of Intracranial artery stenosis and cerebral small vessel disease in general population.

ABSTRACT:

Background

Intracranial artery stenosis (ICAS) and cerebral small vessel disease (CSVD) are associated with a heavy socioeconomic burden; however, their longitudinal changes remain controversial.

Methods

We conducted a longitudinal analysis on 756 participants of Shunyi Cohort who underwent both baseline and follow-up brain magnetic resonance imaging (MRI) and MR angiography in order to investigate the risk factors for ICAS and CSVD progression in community population. Incident ICAS was defined as new stenosis occurring in at least one artery or increased severity of the original artery stenosis. CSVD markers included lacunes, cerebral microbleeds (CMB), and white matter hyperintensities (WMH).

Results

After 5.58 ± 0.49 years of follow-up, 8.5% of the 756 participants

SUBMITTER: Pan ZA 

PROVIDER: S-EPMC11378397 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature