Sleep patterns, genetic susceptibility, and venous thromboembolism: A prospective study of 384,758 UK Biobank participants.

ABSTRACT:

Background

Although healthy sleep patterns have been linked to a lower risk of cardiovascular disease in earlier research, it is unclear how beneficial they are for venous thromboembolism (VTE).

Aim

This research aimed to examine the correlation between sleep patterns, genetic susceptibility, and VTE.

Methods

In the UK Biobank cohort, healthy sleep behaviors were defined as early chronotype, 7-8 hours of sleep each day, no snoring, infrequent insomnia, and infrequent daytime sleepiness. Each of the five criteria was given 1 point, creating a healthy sleep score ranging from 0 to 5. Cox proportional hazards regression models were utilized to examine the associations between genetic susceptibility, healthy sleep score and VTE.

Results

The UK Biobank study include

SUBMITTER: Bai J 

PROVIDER: S-EPMC11379228 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature