Impact of scattering phase function and polarization on the accuracy of diffuse and sub-diffuse spatial frequency domain imaging.

ABSTRACT:

Significance

Although spatial frequency domain imaging (SFDI) has been well characterized under diffuse optical conditions, tissue measurements made outside the diffuse regime can provide new diagnostic information. Before such measurements can become clinically relevant, however, the behavior of sub-diffuse SFDI and its effect on the accuracy of derived tissue parameters must be assessed.

Aim

We aim to characterize the impact that both the assumed scattering phase function (SPF) and the polarization state of the illumination light source have on the accuracy of SFDI-derived optical properties when operating under diffuse or sub-diffuse conditions, respectively.

Approach

Through the use of a set of well-characterized optical phantoms, SFDI accuracy was assessed at fou

SUBMITTER: Walter AB 

PROVIDER: S-EPMC11379407 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature