High-quality identification of volatile organic compounds (VOCs) originating from breath.

ABSTRACT:

Introduction

Volatile organic compounds (VOCs) can arise from underlying metabolism and are detectable in exhaled breath, therefore offer a promising route to non-invasive diagnostics. Robust, precise, and repeatable breath measurement platforms able to identify VOCs in breath distinguishable from background contaminants are needed for the confident discovery of breath-based biomarkers.

Objectives

To build a reliable breath collection and analysis method that can produce a comprehensive list of known VOCs in the breath of a heterogeneous human population.

Methods

The analysis cohort consisted of 90 pairs of breath and background samples collected from a heterogenous population. Owlstone Medical's Breath Biopsy^® OMNI^® platform, consisting of sampl

SUBMITTER: Arulvasan W 

PROVIDER: S-EPMC11379754 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature