Which Gait Tasks Produce Reliable Outcome Measures of Freezing of Gait in Parkinson's Disease?

ABSTRACT:

Background

Measurement of freezing of gait (FOG) relies on the sensitivity and reliability of tasks to provoke FOG. It is currently unclear which tasks provide the best outcomes and how medication state plays into this.

Objective

To establish the sensitivity and test-retest reliability of various FOG-provoking tasks for presence and severity of FOG, with (ON) and without (OFF) dopaminergic medication.

Methods

FOG-presence and percentage time frozen (% TF) were derived from video annotations of a home-based FOG-provoking protocol performed in OFF and ON. This included: the four meter walk (4MW), Timed Up and Go (TUG) single (ST) and dual task (DT), 360° turns in ST and DT, a doorway condition, and a personalized condition. Sensitivity was tested at baseline in 63 defin

SUBMITTER: Zoetewei D 

PROVIDER: S-EPMC11380302 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature