Distributed management of patient data-sharing informed consents for clinical research.

ABSTRACT:

Background

The consent protocol is now a critical part in the overall orchestration of clinical research. We aimed to demonstrate the feasibility of an Ethereum-based informed consent system, which includes an immutable and automated channel of consent matching, to simultaneously assure patient privacy and increase the efficiency of researchers' data access.

Method

We simulated a multi-site scenario, each assigned 10000 consent records. A consent record contained one patient's data-sharing preference with regards to seven data categories. We developed a blockchain-based infrastructure with a smart contract to record consents on-chain, and to query consenting patients corresponding to specific criteria. We measured our system's recording efficiency against a baseline design a

SUBMITTER: Pham A 

PROVIDER: S-EPMC11380755 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature