Consumption of different types of meat and the risk of chronic limb-threatening ischemia: the Singapore Chinese Health Study.

ABSTRACT:

Background

Although red meat consumption has been associated with risk of atherosclerotic coronary artery disease and stroke, no prospective study has examined this with the risk of chronic limb-threatening ischemia (CLTI).

Methods

In a prospective study of 63,257 Chinese in Singapore, who were aged 45-74 years old at recruitment, diet was assessed via a validated semi-quantitative food frequency questionnaire. Incident CLTI cases were ascertained via linkage with nationwide hospital records for lower extremity amputation or angioplasty for peripheral arterial disease. Multivariable Cox models were used to examine associations between quartiles of meat intake and CLTI risk.

Results

After a mean follow-up of 18.8 years, there were 1069 cases of CLTI. Higher intake of r

SUBMITTER: Ying AF 

PROVIDER: S-EPMC11380768 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature