Hospital variation in adoption of balanced transfusion practices among injured patients requiring blood transfusions.

ABSTRACT:

Background

This study sought to measure hospital variability in adoption of balanced transfusion following the Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) guidelines. We hypothesized hospital adoption rates of balanced transfusion would be low, and vary significantly among hospitals after controlling for patient, injury and hospital characteristics.

Study design and methods

This was an observational cohort study of injured adult patients (≥16 years) in Trauma Quality Improvement Program hospitals 2016-2021. Inclusion criteria were hypotensive patients receiving one transfusion of packed red blood cells, fresh frozen plasma, platelets, or cryoprecipitate. Balanced transfusion was defined as ≥1 ratio of plasma to packed red blood cells or platelets to pac

SUBMITTER: Nasca B 

PROVIDER: S-EPMC11381157 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature