Abnormal activation patterns in MT+ during visual motion perception in major depressive disorder.

ABSTRACT:

Objective

Previous studies have found that patients with Major Depressive Disorder (MDD) exhibit impaired visual motion perception capabilities, and multi-level abnormalities in the human middle temporal complex (MT+), a key brain area for processing visual motion information. However, the brain activity pattern of MDD patients during the perception of visual motion information is currently unclear. In order to study the effect of depression on the activity and functional connectivity (FC) of MT+ during the perception of visual motion information, we conducted a study combining task-state fMRI and psychophysical paradigm to compare MDD patients and healthy control (HC).

Methods

Duration threshold was examined through a visual motion perception psychophysical experiment. In a

SUBMITTER: Liu DY 

PROVIDER: S-EPMC11381256 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature