Meta-analysis of hybrid immunity to mitigate the risk of Omicron variant reinfection.

ABSTRACT:

Background

Hybrid immunity (a combination of natural and vaccine-induced immunity) provides additional immune protection against the coronavirus disease 2019 (COVID-19) reinfection. Today, people are commonly infected and vaccinated; hence, hybrid immunity is the norm. However, the mitigation of the risk of Omicron variant reinfection by hybrid immunity and the durability of its protection remain uncertain. This meta-analysis aims to explore hybrid immunity to mitigate the risk of Omicron variant reinfection and its protective durability to provide a new evidence-based basis for the development and optimization of immunization strategies and improve the public's awareness and participation in COVID-19 vaccination, especially in vulnerable and at-risk populations.

Methods

Emb

SUBMITTER: Zheng H 

PROVIDER: S-EPMC11381385 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature