Detection of inflammation by whole-body MRI in young people with juvenile idiopathic arthritis.

ABSTRACT:

Objectives

To assess the frequency of joint inflammation detected by whole-body MRI (WBMRI) in young people (YP) with JIA and controls, and to determine the relationship between WBMRI-detected inflammation and clinical findings.

Methods

YP aged 14-24 years, with JIA (patients) or arthralgia without JIA (controls), recruited from one centre, underwent a WBMRI scan after formal clinical assessment. Consensus between at least two of the three independent radiologists was required to define inflammation and damage on WBMRI, according to predefined criteria. YP with JIA were deemed clinically active as per accepted definitions. The proportions of YP with positive WBMRI scans for joint inflammation (one or more inflamed joint) as well as serum biomarkers were compared between acti

SUBMITTER: Choida V 

PROVIDER: S-EPMC11381681 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature