Identifying combinations of long-term conditions associated with sarcopenia: a cross-sectional decision tree analysis in the UK Biobank study.

ABSTRACT:

Objectives

This study aims to determine whether machine learning can identify specific combinations of long-term conditions (LTC) associated with increased sarcopenia risk and hence address an important evidence gap-people with multiple LTC (MLTC) have increased risk of sarcopenia but it has not yet been established whether this is driven by specific combinations of LTC.

Design

Decision trees were used to identify combinations of LTC associated with increased sarcopenia risk. Participants were classified as being at risk of sarcopenia based on maximum grip strength of <32 kg for men and <19 kg for women. The combinations identified were triangulated with logistic regression.

Setting

UK Biobank.

Participants

UK Biobank participants with MLTC (two or more LTC) at

SUBMITTER: Hillman SJ 

PROVIDER: S-EPMC11381693 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature