Associations of serum 25-hydroxyvitamin D with hsCRP and other novel inflammatory biomarkers in children: a cross-sectional study.

ABSTRACT:

Objective

Previous studies have shown the anti-inflammatory effect of 25-hydroxyvitamin D (25(OH)D) and the crucial roles of high-sensitive C reactive protein (hsCRP) and novel inflammatory markers (red blood cell distribution width-platelet count ratio (RDWPCR), mean platelet volume-platelet count ratio (MPVPCR), neutrophil-lymphocyte ratio (NLR) and white blood cell-neutrophil ratios (WBCNR)) in several diseases, but scarce data explored the associations of 25(OH)D with hsCRP and novel inflammatory markers. This study aimed to investigate these associations in children.

Design

Cross-sectional study.

Setting

Children in China.

Participants

10141 children (mean age 14.6 months) were included.

Primary and secondary outcome measures

HsCRP, red blood cell d

SUBMITTER: Dong H 

PROVIDER: S-EPMC11381719 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature