Simultaneous clonal spread of NDM-1-producing Pseudomonas aeruginosa ST773 from Ukrainian patients in the Netherlands and Spain.

ABSTRACT:

Objectives

We describe the clonal spread of New Delhi metallo-β-lactamase (NDM) 1-producing Pseudomonas aeruginosa isolates belonging to the ST773 clone in Spain and the Netherlands, associated with the transfer of Ukrainian patients during the war.

Methods

Between March and December 2022, nine NDM-1-producing P. aeruginosa ST773 isolates were recovered from nine Ukrainian patients evacuated to two Spanish (n = 3) and five Dutch (n = 6) hospitals. Antimicrobial susceptibility testing was studied (Sensititre, Microscan, EUCAST-2023). Whole genome sequencing (Illumina, Oxford-Nanopore) was used to analyze the genetic relatedness, the resistome, and the prophage content.

Results

All NDM-1-producing P. aeruginosa ST773 isolates exhibited

SUBMITTER: Hernandez-Garcia M 

PROVIDER: S-EPMC11381890 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature