Association between interleukin-6 levels and stroke: a systematic review and meta-analysis.

ABSTRACT:

Objectives

We aimed to evaluate the association of interleukin-6 (IL-6) expression levels with stroke.

Methods

According to the set search strategy, we systematically screened relevant studies using PubMed and extracted study results regarding IL-6 from the literature for comprehensive quantitative analysis to explore the relationship between IL-6 level and stroke risk.

Results

This study included 15 publications with a total of 1696 participants, with 975 cases in the case group and 721 cases in the control group. Meta-analysis showed that IL-6 levels were significantly higher in the stroke population than those in the control group (standardized mean difference = 1.22, 95% confidence interval = 0.79-1.64). Subgroup analysis showed that there was no significant diffe

SUBMITTER: Huang X 

PROVIDER: S-EPMC11382220 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature