The impact of zwitterionic surfactants on optode-based nanosensors via different fabrication approaches and sensing mechanisms.

ABSTRACT: In this work, we explored the impact of zwitterionic surfactants, sulfobetaine 16 (SB-16) and a PEG-phospholipid conjugate (DSPE-PEG), on nanosensor performance. We fabricated four sensors (for Na⁺, K⁺, Al³⁺, and O₂) and examined how these surfactants influenced various aspects, including fabrication methods, sensing mechanisms, and the incorporation of nanomaterials. Our results highlighted SB-16's role in enhancing selectivity in ion-exchange sensors (Na⁺ and K⁺) while maintaining sensitivity akin to its PEG counterpart. The liquid-liquid extraction based sensors (Al³⁺) were unaffected by surfactant choice, while the O₂ sensors that operate via collisional quenching exhibited reduced sensitivit

SUBMITTER: Mendonsa AA 

PROVIDER: S-EPMC11382340 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature