Analysis of secondary metabolites and morphology in Streptomyces rimosus microparticle-enhanced cultivation (MPEC) at various initial organic nitrogen concentrations.

ABSTRACT: The influence of talc microparticles on metabolism and morphology of S. rimosus at various initial organic nitrogen concentrations was investigated. The shake flask cultivations were conducted in the media with yeast extract (nitrogen source) concentration equal to 1 g YE L^- 1 and 20 g YE L^- 1. Two talc microparticle concentrations of 5 g TALC L^- 1 and 10 g TALC L^- 1 were tested in microparticle-enhanced cultivation (MPEC) runs. A high nitrogen concentration of 20 g YE L^- 1 promoted the development of small agglomerates (pellets) of projected area lower than 10⁵ µm² and dispersed pseudohyphae. A low nitrogen concentration of 1 g YE L^- 1 led to the limitation of S. rimosus growth and, in consequence, the

SUBMITTER: Scigaczewska A 

PROVIDER: S-EPMC11382385 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature