Association between polypharmacy and 2-year outcomes among Chinese older inpatients: a multi-center cohort study.

ABSTRACT:

Background

The escalating global prevalence of polypharmacy presents a growing challenge to public health. In light of this issue, the primary objective of our study was to investigate the status of polypharmacy and its association with clinical outcomes in a large sample of hospitalized older patients aged 65 years and over.

Methods

A two-year prospective cohort study was carried out at six tertiary-level hospitals in China. Polypharmacy was defined as the prescription of 5 or more different medications daily, including over-the-counter and non-prescription medications. Baseline polypharmacy, multimorbidity, and other variables were collected when at admission, and 2-year outcomes were recorded by telephone follow-up. We used multivariate logistic regression analysis to exa

SUBMITTER: Liu X 

PROVIDER: S-EPMC11382416 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature