Incidence and risk factors for colorectal cancer in Africa: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. There is a significant burden of mortality from colorectal cancer in Africa. Due to the heterogeneity of dietary and lifestyle practices throughout Africa, our work sought to define risk factors for the development of CRC in the African continent.

Methods

We systematically searched PubMed, Embase, Global Health, CINAHL, Cochrane CENTRAL, and African Index Medicus for studies written in English, examining the incidence and risk factors of CRC in Africa. A systematic analysis was done to compare different risk factors in constituent studies. A meta-analysis random effects model was fitted to estimate the pooled incidence of CRC.

Results

Of 2471 studies screened, 26 were i

SUBMITTER: Tazinkeng NN 

PROVIDER: S-EPMC11382465 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature