Relationship between mixed exposure to phenyl hydroxides, polycyclic aromatic hydrocarbons, and phthalates and the risk of arthritis.

ABSTRACT:

Background

To determine the relationship between mixed exposure to three types of endocrine-disrupting chemicals (EDCs), namely phenyl hydroxides, polycyclic aromatic hydrocarbons (PAHs), and phthalates (PAEs), and risk of arthritis.

Methods

Participants were selected from National Health and Nutrition Examination Survey (NHANES). The relationships between the urinary concentrations of phenyl hydroxides, PAHs, and PAEs and the risk of arthritis were analyzed by generalized linear regression model. The mixed exposure to these EDCs and the risk of arthritis was analyzed by weighted quantile sums (WQSs) and Bayesian kernel machine regression (BKMR) model.

Results

Our analysis showed that participants with urinary benzophenone-3 and methylparaben concentrations in the hig

SUBMITTER: Fu Q 

PROVIDER: S-EPMC11382499 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature