Host genetics and gut microbiota synergistically regulate feed utilization in egg-type chickens.

ABSTRACT:

Background

Feed efficiency is a crucial economic trait in poultry industry. Both host genetics and gut microbiota influence feed efficiency. However, the associations between gut microbiota and host genetics, as well as their combined contributions to feed efficiency in laying hens during the late laying period, remain largely unclear.

Methods

In total, 686 laying hens were used for whole-genome resequencing and liver transcriptome sequencing. 16S rRNA gene sequencing was conducted on gut chyme (duodenum, jejunum, ileum, and cecum) and fecal samples from 705 individuals. Bioinformatic analysis was performed by integrating the genome, transcriptome, and microbiome to screen for key genetic variations, genes, and gut microbiota associated with feed efficiency.

Results

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SUBMITTER: Zhang W 

PROVIDER: S-EPMC11382517 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature