Diagnosis of Progressive Multiple Sclerosis From the Imaging Perspective: A Review.

ABSTRACT:

Importance

Although magnetic resonance imaging (MRI) is useful for monitoring disease dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there has been less application of MRI to progressive MS, including diagnosing primary progressive (PP) MS and identifying patients with relapsing-remitting (RR) MS who are at risk of developing secondary progressive (SP) MS. This review addresses clinical application of MRI for both diagnosis and prognosis of progressive MS.

Observations

Although nonspecific, some spinal cord imaging features (diffuse abnormalities and lesions involving gray matter [GM] and ≥2 white matter columns) are typical of PPMS. In patients with PPMS and those with relapse-onset MS, location of lesions in critical central nervous syst

SUBMITTER: Filippi M 

PROVIDER: S-EPMC11382596 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature