Natural Language Processing Applied to Spontaneous Recall of Famous Faces Reveals Memory Dysfunction in Temporal Lobe Epilepsy Patients.

ABSTRACT:

Objective and background

Epilepsy patients rank memory problems as their most significant cognitive comorbidity. Current clinical assessments are laborious to administer and score and may not always detect subtle memory decline. The Famous Faces Task (FF) has robustly demonstrated that left temporal lobe epilepsy (LTLE) patients remember fewer names and biographical details compared to right TLE (RTLE) patients and healthy controls (HCs). We adapted the FF task to capture subjects' entire spontaneous spoken recall, then scored responses using manual and natural language processing (NLP) methods. We expected to replicate previous group level differences using spontaneous speech and semi-automated analysis.

Methods

Seventy-three (N=73) adults (28 LTLE, 18 RTLE, and 27 HCs) wer

SUBMITTER: Tefera E 

PROVIDER: S-EPMC11382998 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature