Computational modeling of left ventricular flow using PC-CMR-derived four-dimensional wall motion.

ABSTRACT: Intracardiac hemodynamics plays a crucial role in the onset and development of cardiac and valvular diseases. Simulations of blood flow in the left ventricle (LV) have provided valuable insight into assessing LV hemodynamics. While fully coupled fluid-solid modelings of the LV remain challenging due to the complex passive-active behavior of the LV wall myocardium, the integration of imaging-driven quantification of structural motion with computational fluid dynamics (CFD) modeling in the LV holds the promise of feasible and clinically translatable characterization of patient-specific LV hemodynamics. In this study, we propose to integrate two magnetic resonance imaging (MRI) modalities with the moving-boundary CFD method to characterize intracardiac LV hemodynamics. Our method uses the sta

SUBMITTER: Peighambari SB 

PROVIDER: S-EPMC11383313 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature