Impact of Cognitive Impairment on Long-Term Outcomes After Transcatheter Aortic Valve Implantation.

ABSTRACT:

Background

Cognitive impairment assessed using the Mini-Mental Status Examination (MMSE) is associated with short-term mortality after transcatheter aortic valve implantation (TAVI). We assessed the long-term prognostic impact of cognitive impairment in patients with severe aortic stenosis post-TAVI.

Methods and results

We enrolled 1,057 consecutive patients who underwent TAVI at the Kokura Memorial Hospital and prospectively assessed them using the MMSE. Results showed that 319 (30%) patients had cognitive impairment. Compared with normal cognition, cognitive impairment was associated with an increased risk for 5-year all-cause mortality (55% vs. 39%; P<0.001), cardiovascular mortality (23% vs. 14%; P=0.007), and non-cardiovascular mortality (42% vs. 29%; P<0.001). Multivar

SUBMITTER: Miyawaki N 

PROVIDER: S-EPMC11383540 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature