A Comparison of Skeletal Muscle Diffusion Tensor Imaging Tractography Seeding Methods.

ABSTRACT: The internal arrangement of a muscle's fibers with respect to its mechanical line of action (muscle architecture) is a major determinant of muscle function. Muscle architecture can be quantified using diffusion tensor magnetic resonance imaging-based tractography, which propagates streamlines from a set of seed points by integrating vectors that represent the direction of greatest water diffusion (and by inference, the local fiber orientation). Previous work has demonstrated that tractography outcomes are sensitive to the method for defining seed points, but this sensitivity has not been fully examined. To do so, we developed a realistic simulated muscle architecture and implemented four novel methods for tract seeding: seeding along the muscle-aponeurosis boundary with an updated procedur

SUBMITTER: Damon BM 

PROVIDER: S-EPMC11383979 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature