<i>Limosilactobacillus reuteri</i> promotes the expression and secretion of enteroendocrine- and enterocyte-derived hormones.

ABSTRACT: Observations that intestinal microbes can beneficially impact host physiology have prompted investigations into the therapeutic usage of such microbes in a range of diseases. For example, the human intestinal microbe Limosilactobacillus reuteri strains ATCC PTA 6475 and DSM 17938 are being considered for use for intestinal ailments including colic, infection, and inflammation as well as non-intestinal ailments including osteoporosis, wound healing, and autism spectrum disorder. While many of their beneficial properties are attributed to suppressing inflammatory responses in the gut, we postulated that L. reuteri may also regulate hormones of the gastrointestinal tract to affect physiology within and outside of the gut. To determine if L. reuteri secreted factors impact

SUBMITTER: Rienzi SCD 

PROVIDER: S-EPMC11384013 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature