Integrating QTL mapping and transcriptomics to decipher the genetic architecture of sterol metabolism in Brassica napus L.

ABSTRACT: Sterols are secondary metabolites commonly found in rapeseed that play crucial physiological roles in plants and also benefit human health. Consequently, unraveling the genetic basis of sterol synthesis in rapeseed is highly important. In this study, 21 individual sterols as well as total sterol (TS) content were detected in a double haploid (DH) population of Brassica napus, and a total of 24 quantitative trait loci (QTL) and 157 mQTL were identified that were associated with TS and different individual sterols. Time-series transcriptomic analysis showed that the differentially expressed genes (DEGs) involved in sterol and lipid biosynthesis pathways were enriched. Additionally, a regulatory network between sterol-related DEGs and transcription factors (TFs) was established using c

SUBMITTER: Xiong Y 

PROVIDER: S-EPMC11384122 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature