Effects of SGLT2 inhibitors on parameters of renal venous congestion in intrarenal Doppler ultrasonography.

ABSTRACT:

Background

Cardiorenal syndrome is a common condition in clinical practice in which renal venous congestion (VC) plays an important role. Intrarenal Doppler ultrasound (IRD) is a non-invasive method to assess and quantify renal VC. The current study aims to investigate the effects of SGLT2 inhibitor (SGLT2i) therapy on IRD parameters of renal VC.

Methods

This prospective observational study included patients with chronic kidney disease (CKD) with or without type 2 diabetes mellitus and/or heart failure (HF) with reduced and preserved ejection fraction who had an indication for standard of care SGLT2i therapy. IRD, assessing venous impedance index (VII), and intrarenal venous flow pattern (IRVF) analysis were performed within the interlobar vessels of the right kidney before

SUBMITTER: Wallbach M 

PROVIDER: S-EPMC11384228 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature