Early cognitive development and psychopathology in children at familial high risk for schizophrenia.

ABSTRACT: Schizophrenia is a neurodevelopmental disorder associated with deficits in cognitive development and childhood psychopathology. Previous studies have focused on older children and the few studies of early childhood have yielded inconsistent findings. We studied cognitive development and psychopathology in children at familial high risk (FHR) of schizophrenia and matched controls from 1 to 6 years and hypothesized that FHR children would show consistent deficits across cognitive and behavioral measures in early childhood.

Study design

Cognitive development in children at high familial risk for schizophrenia or schizoaffective disorder (n = 33) and matched healthy controls (n = 66) was assessed at 1 and 2 years with the Mullen Scales of Early Learning, and at 4 and 6 years with the St

SUBMITTER: Stephens RL 

PROVIDER: S-EPMC11384306 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature