Development and validation of a prediction model for rebound hyperbilirubinemia: a Chinese neonatal cohort study.

ABSTRACT:

Background

Rebound hyperbilirubinemia (HBB) is still present in as high as 10% of newborn babies. However, the applicability of established prediction models for rebound HBB to Chinese newborns is unclear. This study aimed to establish a model to predict HBB rebound after phototherapy among Chinese neonates.

Methods

A retrospective cohort study was conducted on 1,035 HBB infants receiving phototherapy. Rebound HBB was defined as total serum bilirubin (TSB) returning to or above the American Academy of Pediatrics (AAP) phototherapy threshold within 72 hours after the end of phototherapy. The predictive effects of previously published two- and three-variable scores were verified. Neonates were randomly assigned in a 6:4 ratio to the training (n=621) group and the testing (n=41

SUBMITTER: Li H 

PROVIDER: S-EPMC11384426 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature