Tislelizumab for treatment of a pediatric patient with primary mediastinal choriocarcinoma: a case report.

ABSTRACT:

Background

Primary mediastinal choriocarcinoma (PCC) is a rare, highly vascular invasive, and prognostically unfavorable malignant tumor. When occurring outside the gonads, primary choriocarcinoma is commonly found in midline locations such as the mediastinum or retroperitoneum. Currently, there is no standardized treatment strategy for PCC. In the case reported herein, we employed tislelizumab and chemotherapy in the treatment of a patient with PCC, and as in March 2024, the patient remained survive.

Case description

A 15-year-old boy who presented with symptoms of fever and cough for a year. Chest computed tomography (CT) scan showed a relatively large soft tissue shadow in the right upper anterior mediastinum, measuring approximately 5.4 cm × 3.8 cm. The patient's soft ti

SUBMITTER: Hu T 

PROVIDER: S-EPMC11384437 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature